胃肠病学

出版时间:2001-1  出版社:科学出版社  作者:费尔德曼  页数:2046  

内容概要

本书是世界上最权威的关于消化系统疾病诊断、治疗的专著,共有169位世界知名教授参加编写。全书全面描述了消化系统的基础科学,包括近年来被广为重视的分子生物学和细胞生物学,以及临床常见器官疾患的组织病理、病理生理及实验室指标的异常等,系统介绍了多器官疾病(如艾滋病)的诊断、治疗及护理。本书的特点是以导师的形式对消化系统疾病列出问题,并进行了详尽的讨论。    本书可供消化科医师、消化专业研究生生和科研人员学习、研究、收藏。

作者简介

作者:(美国) 费尔德曼(Feldman.M.)

书籍目录

VOLUME 1  Section Ⅰ  Biology of the Gastrointestinal Tract  Section Ⅱ  Approach to Patients with Symptoms and Signs  Section Ⅲ  Nutrition in Gastroenterology  Section Ⅳ  Topics Involving Multiple Organs  Section Ⅴ Esophagus  Section Ⅵ  Stomacch and Duodenum  Section Ⅶ  Pancreas  Section Ⅷ  Biliary TractVOLUME 2  Section Ⅸ  Liver  Section Ⅹ  Smalland Large Intestines  Section Ⅺ  Vasculature and Supporting Structuresindex

章节摘录

The extensive use of immunocytochemistry to localize pep- tides has revealed that individual neurons coexpress and presumably cosecrete multiple peptides,s Furthermore, both peptide and nonpeptide neurotransmitters are invariably coex- pressed. For example, 45% of neurons in the submucosal plexus of the guinea pig intestine coexpress vasoactive intesti- nal polypeptide, dynorphin, galanin, and neuromedin U. What is the physiologic relevance for a neuron to synthesize and possibly release a cocktail of neurotransmitters? In general, this is an unanswered question. However, examination of the neural regulation of salivary secretion has yielded some in- sight into how two neurotransmitters may work together. Para- sympathetic ganglia innervate secretory cells and smooth mus- cle cells of the salivary ducts, and the nerve endings contain acetylcholine in small vesicles and vasoactive intestinal pep- tide in large vesicles. Stimulation induces release of acetylcho- line and vasoactive intestinal peptide and also increases secre- tion and blood flow. These responses to low-frequency stimulation are mediated by acetylcholine, inasmuch as they are enhanced by eserine (acetylcholinesterase inhibitor) and blocked by atropine (muscarinic receptor antagonist). At higher frequencies, both effects are enhanced by eserine, but only salivation is blocked by atropine. Thus vasoactive intesti- nal peptide is released by high-frequency stimulation, wherein it is a vasodilator and may enhance the effect of acetylcholine on secretory cells.

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《胃肠病学(上下册)》是由科学出版社出版的。

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