癌症基因治疗学

出版时间：1899-12  出版社：人民卫生出版社  作者：拉蒂姆  页数：534  字数：1364000  

内容概要

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书籍目录

ContributorPrefacePARTⅠ VECTORS FOR GENE THERAPR OF CANCER  1.Retroviral Vector Design for Cancer Gene Therapy  2.Noninfections Gene Transfer and Expression Systems for Cancer Gene Therapy  3.Parvovirus Vectors for the Gene Therapy of Cancer   4.Antibody-Targeted Gene Therapy  5.Ribozymes in Cancer Gene Therapy  6.The Advent of Lentiviral Vectors:Prospects for Cancer TherapyPART Ⅱ IMMUNE TARGETIED GENE THERAPY  7.Immunologic Targets for the Gene Therapy of CancerPART Ⅱa VACCINE STRATEGIES  8.Development of Eqitope-Specific Immunotherapies for Human Malignancies and Premalignant Lesions Expressing Mutated ras GenesPART Ⅱb DENDRITIC CELL-BASED GENE THERAPY  9.Introduction to Dendritic Cells  10.DNA and Dendritic Cell-Based Genetic Immunization Against Cancer  11.RNA-Transfected Dendritic Cells as ImmunogensPART Ⅱc CYTOKINES AND CO-FACTORS  12.In Situ Immune Modulation Using Recombinatnt Vaccinia Virus Vectors:Preclinical Studies to Clinical Implementation  13.The Use of Particle-Mediated Gene Transfer of Immunotherapy of CancePART Ⅱd GENETICALLY MODIFIED EFFECTOR CELLS FOR IMMUNE-BASED IMMUNOTHERAPY  14.Applications of Gene Transfer in the Adoptive Immunotherapy of Cancer  15.Update on the Use of Genetically Modified Hematoppietic Stem Cells for Cancer TherapyPART Ⅲ ONCOGENE-TARGETED GENE THERAPY  16.CLINICAL Applications of Tumor-Suppressor Gene Therapy  17.Cancer Gene Therapy with Tumor Supperssor Genes Involved in Cell-Cycle Control  18.Cancer Gene Therapy with the p53 Tumor Suppressor Gene   19.Antisense Downregulation of the Apoptosis-Related Bcl-2and Bcl-xl Proteins:A New Approach to Cancer Therapy  20.Gene Therpy for Chronic Myelogenous LeukemiaPART Ⅳ MANULATION OF DRUG RESISTANCE MECHANISMS BY GENE THERARY……PART Ⅴ ANTI-ANIOGENESIS AND PRO-APORTOTIC GENE THERAPYPART Ⅵ PRODRUG ACTIVATION STRATEGIES FOR GENE THERAPY OF CANCERIndex